GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2507
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Dmd
Name: dystrophin
Acc ID: CHEBI:6888
Term: 6alpha-methylprednisolone
Definition: The 6alpha-stereoisomer of 6-methylprednisolone.
Chemical ID: MESH:D008775
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:104796480464CTDMethylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]

Methylprednisolone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA]

PMID:26930420
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.