GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2032
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Adam10
Name: ADAM metallopeptidase domain 10
Acc ID: CHEBI:69355
Term: casticin
Definition: A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii.
Chemical ID: MESH:C054133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:7358486480464CTDcasticin results in increased expression of ADAM10 mRNA

PMID:28444820
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.