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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3845
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tf
Name: transferrin
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:114066480464CTD[Lipopolysaccharides co-treated with Monocrotaline] results in increased expression of TF protein, [Monocrotaline co-treated with Lipopolysaccharides] results in increased secretion of TF protein, TF mRNA affects the reaction [[Monocrotaline co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein], TF mRNA affects the reaction [[Monocrotaline co-treated with Lipopolysaccharides] results in increased secretion of LEP protein]

PMID:21279329, PMID:21327618
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.