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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 733705
Species: Homo sapiens
CRRD Object: Gene
Symbol: CTNNB1
Name: catenin beta 1
Acc ID: CHEBI:70436
Term: platycodin D
Definition: A triterpenoid saponin that has formula C57H92O28.
Chemical ID: MESH:C108953
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:15504666480464CTDCTNNB1 affects the reaction [platycodin D results in decreased expression of CEBPA protein], CTNNB1 affects the reaction [platycodin D results in decreased expression of FABP4 protein], CTNNB1 affects the reaction [platycodin D results in increased expression of CCND1 mRNA], CTNNB1 affects the reaction [platycodin D results in increased expression of PPARG mRNA], platycodin D results in increased expression of and results in increased localization of CTNNB1 protein

PMID:21798269
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.