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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1315197
Species: Homo sapiens
CRRD Object: Gene
Symbol: DHCR24
Name: 24-dehydrocholesterol reductase
Acc ID: CHEBI:7071
Term: N,N-diethyl-m-toluamide
Definition: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.
Chemical ID: MESH:D003671
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13065296480464CTD[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA

PMID:28659758
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.