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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 11250
Species: Mus musculus
CRRD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:73290
Term: PK-11195
Definition: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 1-(2-chlorophenyl)isoquinoline-3-carboxylic acid with the amino group of sec-butylmethylamine
Chemical ID: MESH:C037850
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7369296480464CTD[PK 11195 co-treated with RXRA] results in increased activity of NR1I2 protein, PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]

PMID:21315811
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.