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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 11250
Species: Mus musculus
CRRD Object: Gene
Symbol: Rxra
Name: retinoid X receptor alpha
Acc ID: CHEBI:7590
Term: nitrofen
Definition: An organic molecular entity that has formula C12H7Cl2NO3.
Chemical ID: MESH:C007350
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:36106480464CTDnitrofen results in decreased expression of RXRA protein

PMID:24972641
increases expressionISORGD:36106480464CTDnitrofen results in increased expression of RXRA mRNA

PMID:17270546, PMID:26672737
multiple interactionsISORGD:36106480464CTDTretinoin promotes the reaction [nitrofen results in increased expression of RXRA mRNA]

PMID:26672737
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.