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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2459
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:78330
Term: huperzine A
Definition: A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity.
Chemical ID: MESH:C050426
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases metabolic processingEXP 6480464CTDCYP1A2 protein results in increased metabolism of huperzine A

PMID:12586202
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.