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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 619573
Species: Mus musculus
CRRD Object: Gene
Symbol: Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Acc ID: CHEBI:80230
Term: Potassium 2,6-dihydroxytriazinecarboxylate
Definition: An organic molecular entity that has formula C4H2KN3O4.
Chemical ID: MESH:C489337
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a6decreases expressionEXP 6480464CTDpotassium oxonate results in decreased expression of SLC22A6 mRNA, potassium oxonate results in decreased expression of SLC22A6 protein

PMID:21909718, PMID:22865646, PMID:22967667
Slc22a6multiple interactionsEXP 6480464CTDAllopurinol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], mulberroside A inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Plant Extracts inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], polydatin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA], Quercetin inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein], resveratrol inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]

PMID:21909718, PMID:22865646, PMID:22967667
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.