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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1345966
Species: Homo sapiens
CRRD Object: Gene
Symbol: SLC25A47
Name: solute carrier family 25 member 47
Acc ID: CHEBI:8064
Term: phenformin
Definition: A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis.
Chemical ID: MESH:D010629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13032476480464CTDPhenformin results in increased expression of SLC25A47 mRNA

PMID:31324951
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.