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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1307758
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Aprt
Name: adenine phosphoribosyl transferase
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:13171336480464CTDPhenobarbital affects the expression of APRT mRNA

PMID:19159669
affects expressionISORGD:13171346480464CTDPhenobarbital affects the expression of APRT mRNA

PMID:23091169
increases expressionISORGD:13171346480464CTDPhenobarbital results in increased expression of APRT mRNA

PMID:19482888
multiple interactionsISORGD:13171346480464CTDNR1I3 protein affects the reaction [Phenobarbital results in increased expression of APRT mRNA]

PMID:19482888
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.