Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


CRRD ID: 1309970
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gsta4
Name: glutathione S-transferase alpha 4
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDPhenobarbital results in increased expression of GSTA4 mRNA, Phenobarbital results in increased expression of GSTA4 protein

PMID:19162173, PMID:9794803
multiple interactionsEXP 6480464CTD[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTA4 protein

decreases expressionISORGD:13206016480464CTDPhenobarbital results in decreased expression of GSTA4 mRNA

Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.