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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3202
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Acc ID: CHEBI:81068
Term: Shikonin
Definition: A hydroxy-1,4-naphthoquinone that has formula C16H16O5.
Chemical ID: MESH:C016101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7364006480464CTDshikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of NR4A2 mRNA], shikonin inhibits the reaction [Calcimycin results in increased expression of NR4A2 mRNA]

PMID:25451590
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.