GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2460
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:81505
Term: 1,2,3,4,6,7,8-Heptachlorodibenzodioxin
Definition: A dibenzodioxine that has formula C12HCl7O2.
Chemical ID: MESH:C046839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD1,2,3,4,6,7,8-heptachlorodibenzodioxin results in increased expression of CYP1B1 mRNA

PMID:25654323, PMID:29738842
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.