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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2482
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp7a1
Name: cytochrome P450 family 7 subfamily A member 1
Acc ID: CHEBI:81758
Term: cyproconazole
Definition: A diastereoisomeric mixture composed of the enantiomeric pair (2R,3S)- and (2S,3R)-cyproconazole in ratio 1:1 with the enantiomeric pair (2R,3R)- and (2S,3S)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases.
Chemical ID: MESH:C093628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[cyproconazole co-treated with epoxiconazole] results in increased expression of CYP7A1 mRNA

PMID:29038839
decreases expressionISORGD:692106480464CTDcyproconazole results in decreased expression of CYP7A1 mRNA

PMID:29995386
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.