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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 619573
Species: Mus musculus
CRRD Object: Gene
Symbol: Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Acc ID: CHEBI:81882
Term: Mercuric oxide
Definition: An organic molecular entity that has formula HgO.
Chemical ID: MESH:C019468
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a6multiple interactionsISORGD:6195726480464CTDadipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]], Glutarates inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]], Ketoglutaric Acids inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]], p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]], Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]], Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]], SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine], SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Glutathione], SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]

PMID:12606766
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.