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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1305490
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Runx1t1
Name: RUNX1 partner transcriptional co-repressor 1
Acc ID: CHEBI:8228
Term: pioglitazone
Definition: A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Chemical ID: MESH:C060836
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13135476480464CTD[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RUNX1T1 mRNA

PMID:27935865
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.