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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1583278
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Pilra
Name: paired immunoglobin-like type 2 receptor alpha
Acc ID: CHEBI:8249
Term: piroxicam
Definition: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling.
Chemical ID: MESH:D010894
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13183816480464CTDPiroxicam results in decreased expression of PILRA mRNA

PMID:19192274
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.