GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621511
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Ctsd
Name: cathepsin D
Acc ID: CHEBI:83258
Term: fenamidone
Definition: A member of the class of imidazolones that is 3,5-dihydroimidazol-4-one substituted at position 2 by a methylthiogroup, at position 3 by an anilino group and at position 5 by phenyl and methyl groups (the S-enantiomer). A fungicide effective against Oomycete diseases such as downy mildew and certain leaf spot diseases.
Chemical ID: MESH:C540355
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:7326376480464CTDfenamidone results in increased expression of CTSD mRNA

PMID:27029645
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.