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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 3173
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nfyc
Name: nuclear transcription factor Y subunit gamma
Acc ID: CHEBI:84050
Term: trabectedin
Definition: A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer.
Chemical ID: MESH:C099150
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:109776480464CTDtrabectedin affects the activity of [NFYA protein binds to NFYB protein binds to NFYC protein]

PMID:15961672
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.