GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2933
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
Acc ID: CHEBI:8489
Term: propiconazole
Definition: The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds.
Chemical ID: MESH:C045950
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISOCRRD:108216480464CTDpropiconazole results in increased expression of ITPR1 mRNA

PMID:19363144, PMID:21278054
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.