GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 2460
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:8499
Term: propranolol
Definition: A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Chemical ID: MESH:D011433
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7367656480464CTDPropranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]

PMID:22167199
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.