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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 1323700
Species: Homo sapiens
CRRD Object: Gene
Symbol: CA6
Name: carbonic anhydrase 6
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CA6affects response to substanceEXP 6480464CTDCA6 gene polymorphism affects the susceptibility to Propylthiouracil

PMID:22312435
CA6decreases expressionISORGD:705166480464CTDPropylthiouracil results in decreased expression of CAR6 mRNA

PMID:24780913
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.