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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 736871
Species: Homo sapiens
CRRD Object: Gene
Symbol: DHFR
Name: dihydrofolate reductase
Acc ID: CHEBI:86290
Term: 6-bromoindirubin-3'-oxime
Definition: A member of the class of biindoles that is indirubin substituted at position 6 by a bromo group and in which the keto group at position 3' has undergone condensation with hydroxylamine to form the corresponding oxime.
Chemical ID: MESH:C483321
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[6-bromoindirubin-3'-oxime co-treated with DHFR mRNA] affects the expression of CTNNB1 protein

PMID:19727391
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