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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 730858
Species: Homo sapiens
CRRD Object: Gene
Symbol: IL2
Name: interleukin 2
Acc ID: CHEBI:88249
Term: PD 0325901
Definition: A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).
Chemical ID: MESH:C506614
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDPD 0325901 inhibits the reaction [IL2 protein results in increased expression of KLRK1 protein], PD 0325901 inhibits the reaction [IL2 protein results in increased expression of NCR3 protein], PD 0325901 inhibits the reaction [IL2 protein results in increased secretion of IFNG protein]

PMID:27563819
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.