GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69651
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor 2
Acc ID: CHEBI:91108
Term: SB 431542
Definition: A member of the class of benzamides that is 4-(imidazol-2-yl)benzamide carrying additional 1,3-benzodioxol-5-yl and pyridin-2-yl substituents at positions 4 and 5 respectively on the imidazole ring.
Chemical ID: MESH:C459179
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISOCRRD:7343336480464CTD4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Sodium Fluoride results in increased expression of TGFBR2 mRNA]

PMID:29127033
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.