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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 621032
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Acc ID: CHEBI:94763
Term: 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester
Definition: A benzocycloheptapyridine that has formula C22H23ClN2O2.
Definition Source(s): CAS:79794-75-5, Drug_Central:1605, LINCS:LSM-5891
Chemical ID: MESH:D017336
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7328736480464CTDLoratadine results in increased expression of NR0B2 mRNA

PMID:15342952
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.