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GENE - CHEMICAL INTERACTIONS REPORT

CRRD ID: 69224
Species: Rattus norvegicus
CRRD Object: Gene
Symbol: Gpx3
Name: glutathione peroxidase 3
Acc ID: CHEBI:9747
Term: Triptolide
Definition: An oxacycle that has formula C20H24O6.
Chemical ID: MESH:C001899
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7373826480464CTDtriptolide results in increased expression of GPX3 mRNA

PMID:31241159
multiple interactionsISORGD:7373826480464CTDFenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA]

PMID:31241159
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.