Gene: Acadl (acyl-Coenzyme A dehydrogenase, long-chain) Mus musculus
Symbol: Acadl
Name: acyl-Coenzyme A dehydrogenase, long-chain
Description: This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C12- and C16-acylCoA. In mice, deficiency of this gene can cause sudden death, cardiomyopathy as well as fasting and cold intolerance. [provided by RefSeq, Nov 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA960361; acetyl-Coenzyme A dehydrogenase, long-chain; AU018452; C79855; LCAD; long-chain specific acyl-CoA dehydrogenase, mitochondrial
Homo sapiens (human) : ACADL (acyl-CoA dehydrogenase long chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acadl (acyl-CoA dehydrogenase, long chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acadl (acyl-CoA dehydrogenase long chain)
Pan paniscus (bonobo/pygmy chimpanzee) : ACADL (acyl-CoA dehydrogenase long chain)
Canis lupus familiaris (dog) : ACADL (acyl-CoA dehydrogenase long chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acadl (acyl-CoA dehydrogenase long chain)
Sus scrofa (pig) : ACADL (acyl-CoA dehydrogenase long chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38166,830,839 - 66,863,309 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37166,877,427 - 66,909,841 (-)NCBIGRCm37mm9NCBIm37
MGSCv36166,764,061 - 66,796,475 (-)NCBImm8
Celera167,346,339 - 67,377,289 (-)NCBICelera
Cytogenetic Map1 C3NCBI
cM Map133.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Acadl
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10056
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-04-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.