Gene: Acadl (acyl-Coenzyme A dehydrogenase, long-chain) Mus musculus
Analyze
Symbol: Acadl
Name: acyl-Coenzyme A dehydrogenase, long-chain
Description: This gene encodes a homotetrameric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C12- and C16-acylCoA. In mice, deficiency of this gene can cause sudden death, cardiomyopathy as well as fasting and cold intolerance. [provided by RefSeq, Nov 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA960361; acetyl-Coenzyme A dehydrogenase, long-chain; AU018452; C79855; LCAD; long-chain specific acyl-CoA dehydrogenase, mitochondrial
Orthologs:
Homo sapiens (human) : ACADL (acyl-CoA dehydrogenase long chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Acadl (acyl-CoA dehydrogenase, long chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acadl (acyl-CoA dehydrogenase long chain)
Pan paniscus (bonobo/pygmy chimpanzee) : ACADL (acyl-CoA dehydrogenase long chain)
Canis lupus familiaris (dog) : ACADL (acyl-CoA dehydrogenase long chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acadl (acyl-CoA dehydrogenase long chain)
Sus scrofa (pig) : ACADL (acyl-CoA dehydrogenase long chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38166,830,839 - 66,863,309 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37166,877,427 - 66,909,841 (-)NCBIGRCm37mm9NCBIm37
MGSCv36166,764,061 - 66,796,475 (-)NCBImm8
Celera167,346,339 - 67,377,289 (-)NCBICelera
Cytogenetic Map1 C3NCBI
cM Map133.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Acadl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10056
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-04-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.