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Gene: ACLY (ATP citrate lyase) Homo sapiens
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Symbol: ACLY
Name: ATP citrate lyase
Description: Exhibits ATP citrate synthase activity. Involved in acetyl-CoA biosynthetic process; carboxylic acid metabolic process; and lipid biosynthetic process. Localizes to the cytosol; nucleoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACL; ATP citrate synthase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPCL; citrate cleavage enzyme; CLATP
Orthologs:
Mus musculus (house mouse) : Acly (ATP citrate lyase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acly (ATP citrate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acly (ATP citrate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ACLY (ATP citrate lyase)
Canis lupus familiaris (dog) : ACLY (ATP citrate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acly (ATP citrate lyase)
Sus scrofa (pig) : ACLY (ATP citrate lyase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,866,916 - 41,930,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371740,023,169 - 40,086,795 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,276,705 - 37,328,798 (-)NCBINCBI36hg18NCBI36
Build 341737,276,706 - 37,328,798NCBI
Celera1736,674,340 - 36,725,809 (-)NCBI
Cytogenetic Map17q21.2NCBI
HuRef1735,785,140 - 35,836,956 (-)NCBIHuRef
CHM1_11740,258,585 - 40,311,003 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ACLY
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10065
Created: 2000-05-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.