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Gene: ACO1 (aconitase 1) Homo sapiens
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Symbol: ACO1
Name: aconitase 1
Description: Exhibits aconitate hydratase activity; iron-responsive element binding activity; and iron-sulfur cluster binding activity. Involved in citrate metabolic process and response to iron(II) ion. Localizes to several cellular components, including the Golgi apparatus; endoplasmic reticulum; and mitochondrion.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aconitase 1, soluble; aconitate hydratase; aconitate hydratase, cytoplasmic; ACONS; citrate hydro-lyase; cytoplasmic aconitase; cytoplasmic aconitate hydratase; cytosplasmic aconitase; epididymis luminal protein 60; ferritin repressor protein; HEL60; IRE-BP 1; IREB1; IREBP; IREBP1; iron regulatory protein 1; iron-responsive element binding protein 1; iron-responsive element-binding protein; iron-responsive element-binding protein 1; IRP1; soluble aconitase
Orthologs:
Mus musculus (house mouse) : Aco1 (aconitase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aco1 (aconitase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aco1 (aconitase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACO1 (aconitase 1)
Canis lupus familiaris (dog) : ACO1 (aconitase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aco1 (aconitase 1)
Sus scrofa (pig) : ACO1 (aconitase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38932,384,603 - 32,454,769 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37932,384,601 - 32,450,834 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36932,374,650 - 32,440,830 (+)NCBINCBI36hg18NCBI36
Build 34932,374,649 - 32,440,830NCBI
Celera932,314,541 - 32,380,796 (+)NCBI
Cytogenetic Map9p21.1ENTREZGENE
HuRef932,340,337 - 32,406,624 (+)NCBIHuRef
CHM1_1932,384,455 - 32,450,692 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on ACO1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10067
Created: 2000-05-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.