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Gene: Actg2 (actin, gamma 2, smooth muscle, enteric) Mus musculus
Symbol: Actg2
Name: actin, gamma 2, smooth muscle, enteric
Description: Predicted to have ATP binding activity. Localizes to cell periphery. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Is expressed in genitourinary system and upper jaw incisor. Orthologous to human ACTG2 (actin gamma 2, smooth muscle); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Act-4; Act4; ACTA3; actin, gamma-enteric smooth muscle; alpha-actin-3; gamma-2-actin; SMGA; smooth muscle gamma-actin
Homo sapiens (human) : ACTG2 (actin gamma 2, smooth muscle)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Actg2 (actin gamma 2, smooth muscle)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actg2 (actin gamma 2, smooth muscle)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTG2 (actin gamma 2, smooth muscle)
Canis lupus familiaris (dog) : ACTG2 (actin gamma 2, smooth muscle)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actg2 (actin gamma 2, smooth muscle)
Sus scrofa (pig) : ACTG2 (actin gamma 2, smooth muscle)
Chlorocebus sabaeus (African green monkey) : ACTG2 (actin gamma 2, smooth muscle)
Heterocephalus glaber (naked mole-rat) : Actg2 (actin gamma 2, smooth muscle)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl683,512,905 - 83,536,265 (-)EnsemblGRCm38mm10GRCm38
GRCm38683,512,909 - 83,536,251 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37683,462,903 - 83,486,245 (-)NCBIGRCm37mm9NCBIm37
MGSCv36683,478,568 - 83,501,883 (-)NCBImm8
Celera685,494,063 - 85,517,393 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Actg2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10077
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.