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Gene: Adcy6 (adenylate cyclase 6) Mus musculus
Symbol: Adcy6
Name: adenylate cyclase 6
Description: Exhibits calcium- and calmodulin-responsive adenylate cyclase activity and scaffold protein binding activity. Involved in several processes, including cAMP biosynthetic process; cellular response to forskolin; and cellular response to vasopressin. Localizes to the intrinsic component of plasma membrane. Predicted to colocalize with the sarcolemma. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Is expressed in several structures, including cardiovascular system; foregut; genitourinary system; nervous system; and respiratory system. Orthologous to human ADCY6 (adenylate cyclase 6); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; glucagon signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AC6; adenylate cyclase type 6; adenylate cyclase type VI; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase; mKIAA0422
Homo sapiens (human) : ADCY6 (adenylate cyclase 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adcy6 (adenylate cyclase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy6 (adenylate cyclase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY6 (adenylate cyclase 6)
Canis lupus familiaris (dog) : ADCY6 (adenylate cyclase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy6 (adenylate cyclase 6)
Sus scrofa (pig) : ADCY6 (adenylate cyclase 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381598,589,978 - 98,610,287 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371598,420,409 - 98,438,064 (-)NCBIGRCm37mm9NCBIm37
MGSCv361598,418,012 - 98,435,667 (-)NCBImm8
Celera15100,737,585 - 100,755,761 (-)NCBICelera
Cytogenetic Map15 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adcy6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10083
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.