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Gene: Adra2a (adrenergic receptor, alpha 2a) Mus musculus
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Symbol: Adra2a
Name: adrenergic receptor, alpha 2a
Description: Exhibits adrenergic receptor activity. Involved in G protein-coupled receptor signaling pathway; fear response; and regulation of synaptic vesicle exocytosis. Localizes to the dopaminergic synapse. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; autopod; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human ADRA2A (adrenoceptor alpha 2A); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adra-2; Adra-2a; alpha(2A)AR; alpha-2A adrenergic receptor; alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha-2AAR; alpha2-C10; alpha2A; alpha2A-adrenergic receptor; alpha2A-AR; AW122659; subtype alpha2-C10
Orthologs:
Homo sapiens (human) : ADRA2A (adrenoceptor alpha 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adra2a (adrenoceptor alpha 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2a (adrenoceptor alpha 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2A (adrenoceptor alpha 2A)
Canis lupus familiaris (dog) : ADRA2A (adrenoceptor alpha 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2a (adrenoceptor alpha 2A)
Sus scrofa (pig) : ADRA2A (adrenoceptor alpha 2A)
Chlorocebus sabaeus (green monkey) : ADRA2A (adrenoceptor alpha 2A)
Heterocephalus glaber (naked mole-rat) : Adra2a (adrenoceptor alpha 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1954,044,151 - 54,048,982 (+)Ensembl
GRCm381954,045,259 - 54,048,982 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371954,119,672 - 54,123,472 (+)NCBIGRCm37mm9NCBIm37
MGSCv361954,098,545 - 54,102,294 (+)NCBImm8
Celera1956,240,003 - 56,243,840 (+)NCBICelera
Cytogenetic Map19 D2NCBI
cM Map1949.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adra2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10098
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.