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Gene: Adra2a (adrenergic receptor, alpha 2a) Mus musculus
Symbol: Adra2a
Name: adrenergic receptor, alpha 2a
Description: Exhibits adrenergic receptor activity. Involved in G protein-coupled receptor signaling pathway; fear response; and regulation of synaptic vesicle exocytosis. Localizes to the dopaminergic synapse. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; autopod; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human ADRA2A (adrenoceptor alpha 2A); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adra-2; Adra-2a; alpha(2A)AR; alpha-2A adrenergic receptor; alpha-2A adrenoceptor; alpha-2A adrenoreceptor; alpha-2AAR; alpha2-C10; alpha2A; alpha2A-adrenergic receptor; alpha2A-AR; AW122659; subtype alpha2-C10
Homo sapiens (human) : ADRA2A (adrenoceptor alpha 2A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adra2a (adrenoceptor alpha 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2a (adrenoceptor alpha 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2A (adrenoceptor alpha 2A)
Canis lupus familiaris (dog) : ADRA2A (adrenoceptor alpha 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2a (adrenoceptor alpha 2A)
Sus scrofa (pig) : ADRA2A (adrenoceptor alpha 2A)
Chlorocebus sabaeus (green monkey) : ADRA2A (adrenoceptor alpha 2A)
Heterocephalus glaber (naked mole-rat) : Adra2a (adrenoceptor alpha 2A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1954,044,151 - 54,048,982 (+)Ensembl
GRCm381954,045,259 - 54,048,982 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371954,119,672 - 54,123,472 (+)NCBIGRCm37mm9NCBIm37
MGSCv361954,098,545 - 54,102,294 (+)NCBImm8
Celera1956,240,003 - 56,243,840 (+)NCBICelera
Cytogenetic Map19 D2NCBI
cM Map1949.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Adra2a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10098
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.