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Gene: Adra2b (adrenergic receptor, alpha 2b) Mus musculus
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Symbol: Adra2b
Name: adrenergic receptor, alpha 2b
Description: Exhibits alpha2-adrenergic receptor activity. Involved in G protein-coupled receptor signaling pathway; MAPK cascade; and angiogenesis. Predicted to localize to cell surface and integral component of plasma membrane. Human ortholog(s) of this gene implicated in diabetic neuropathy; hypertension; myocardial infarction; obesity; and type 2 diabetes mellitus. Is expressed in several structures, including adrenal gland; central nervous system; liver; and retina. Orthologous to human ADRA2B (adrenoceptor alpha 2B); INTERACTS WITH 1,1-dichloroethene; 4,4'-sulfonyldiphenol; acetylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: [a]2B; a2b-AR; Adra-2b; alpha-2B adrenergic receptor; alpha-2B adrenoceptor; alpha-2B adrenoreceptor; alpha-2BAR; alpha2-C2; alpha2B; subtype alpha2-C2
Orthologs:
Homo sapiens (human) : ADRA2B (adrenoceptor alpha 2B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Adra2b (adrenoceptor alpha 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adra2b (adrenoceptor alpha 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRA2B (adrenoceptor alpha 2B)
Canis lupus familiaris (dog) : ADRA2B (adrenoceptor alpha 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adra2b (adrenoceptor alpha 2B)
Sus scrofa (pig) : ADRA2B (adrenoceptor alpha 2B)
Chlorocebus sabaeus (African green monkey) : ADRA2B (adrenoceptor alpha 2B)
Heterocephalus glaber (naked mole-rat) : Adra2b (adrenoceptor alpha 2B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl2127,363,208 - 127,367,221 (+)EnsemblGRCm38mm10GRCm38
GRCm382127,363,179 - 127,367,221 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372127,189,022 - 127,192,957 (+)NCBIGRCm37mm9NCBIm37
MGSCv362127,054,727 - 127,058,662 (+)NCBImm8
Celera2128,605,637 - 128,609,581 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Adra2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10101
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.