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Gene: Aldob (aldolase B, fructose-bisphosphate) Mus musculus
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Symbol: Aldob
Name: aldolase B, fructose-bisphosphate
Description: Exhibits fructose-1-phosphate aldolase activity and fructose-bisphosphate aldolase activity. Predicted to be involved in several processes, including NADH oxidation; fructose 1,6-bisphosphate metabolic process; and vacuolar proton-transporting V-type ATPase complex assembly. Predicted to localize to several cellular components, including centriolar satellite; endoplasmic reticulum membrane; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and olfactory epithelium. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Aldo-2; Aldo2; aldolase 2, B isoform; BC016435; fructose-bisphosphate aldolase B; liver-type aldolase; MGC36398
Orthologs:
Homo sapiens (human) : ALDOB (aldolase, fructose-bisphosphate B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aldob (aldolase, fructose-bisphosphate B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldob (aldolase, fructose-bisphosphate B)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDOB (aldolase, fructose-bisphosphate B)
Canis lupus familiaris (dog) : ALDOB (aldolase, fructose-bisphosphate B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldob (aldolase, fructose-bisphosphate B)
Sus scrofa (pig) : ALDOB (aldolase, fructose-bisphosphate B)
Chlorocebus sabaeus (African green monkey) : ALDOB (aldolase, fructose-bisphosphate B)
Heterocephalus glaber (naked mole-rat) : Aldob (aldolase, fructose-bisphosphate B)
more info ...
Related Pseudogenes: Gm15172  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl449,535,995 - 49,549,546 (-)EnsemblGRCm38mm10GRCm38
GRCm38449,535,993 - 49,549,546 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37449,548,867 - 49,562,355 (-)NCBIGRCm37mm9NCBIm37
MGSCv36449,557,095 - 49,570,583 (-)NCBImm8
Celera449,564,249 - 49,577,800 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.57NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Aldob
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10140
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.