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Gene: Speg (SPEG complex locus) Mus musculus
Symbol: Speg
Name: SPEG complex locus
Description: Predicted to have protein kinase activity. Involved in circulatory system development; in utero embryonic development; and respiratory system development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in centronuclear myopathy 5. Is expressed in arterial blood vessel; heart; and trachea. Orthologous to human SPEG (striated muscle enriched protein kinase).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aortic preferentially expressed gene 1; aortic preferentially expressed protein 1; APEG-1; Apeg1; AW125581; BPEG; D1Bwg1450e; mKIAA1297; SPEGalpha; SPEGbeta; striated muscle-specific serine/threonine-protein kinase
Homo sapiens (human) : SPEG (striated muscle enriched protein kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Speg (striated muscle enriched protein kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Speg (striated muscle enriched protein kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : SPEG (striated muscle enriched protein kinase)
Canis lupus familiaris (dog) : SPEG (striated muscle enriched protein kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Speg (striated muscle enriched protein kinase)
Sus scrofa (pig) : SPEG (striated muscle enriched protein kinase)
Chlorocebus sabaeus (African green monkey) : SPEG (striated muscle enriched protein kinase)
Heterocephalus glaber (naked mole-rat) : Speg (striated muscle enriched protein kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl175,375,297 - 75,432,320 (+)EnsemblGRCm38mm10GRCm38
GRCm38175,375,297 - 75,432,320 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37175,371,872 - 75,428,889 (+)NCBIGRCm37mm9NCBIm37
MGSCv36175,258,445 - 75,315,462 (+)NCBImm8
Celera175,865,860 - 75,923,244 (+)NCBICelera
Cytogenetic Map1C4NCBI
cM Map138.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Speg
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10167
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.