Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Apoc3 (apolipoprotein C-III) Mus musculus
Symbol: Apoc3
Name: apolipoprotein C-III
Description: Predicted to have high-density lipoprotein particle receptor binding activity; lipase inhibitor activity; and phospholipid binding activity. Involved in cholesterol metabolic process; triglyceride catabolic process; and triglyceride mobilization. Predicted to localize to the chylomicron; spherical high-density lipoprotein particle; and triglyceride-rich plasma lipoprotein particle. Human ortholog(s) of this gene implicated in chronic kidney disease; cognitive disorder; coronary artery disease; familial hyperlipidemia (multiple); and glucose metabolism disease (multiple). Orthologous to human APOC3 (apolipoprotein C3).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apo-CIII; Apoc; apoC-III; apolipoprotein C3
Homo sapiens (human) : APOC3 (apolipoprotein C3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apoc3 (apolipoprotein C3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoc3 (apolipoprotein C3)
Pan paniscus (bonobo/pygmy chimpanzee) : APOC3 (apolipoprotein C3)
Canis lupus familiaris (dog) : APOC3 (apolipoprotein C3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoc3 (apolipoprotein C3)
Sus scrofa (pig) : APOC3 (apolipoprotein C3)
Chlorocebus sabaeus (African green monkey) : APOC3 (apolipoprotein C3)
Heterocephalus glaber (naked mole-rat) : Apoc3 (apolipoprotein C3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl946,232,933 - 46,235,636 (-)EnsemblGRCm38mm10GRCm38
GRCm38946,233,050 - 46,235,636 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37946,041,134 - 46,043,380 (-)NCBIGRCm37mm9NCBIm37
MGSCv36945,984,046 - 45,986,292 (-)NCBImm8
Celera943,522,001 - 43,524,576 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map925.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Apoc3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10179
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.