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Gene: Aqp1 (aquaporin 1) Mus musculus
Symbol: Aqp1
Name: aquaporin 1
Description: Exhibits ephrin receptor binding activity; potassium ion transmembrane transporter activity; and water transmembrane transporter activity. Involved in several processes, including corticotropin secretion; glomerular filtration; and metanephros development. Localizes to several cellular components, including basal plasma membrane; extracellular exosome; and symbiont-containing vacuole. Predicted to colocalize with symbiont-containing vacuole membrane. Is expressed in several structures, including alimentary system; metanephros; sensory organ; skeleton; and ureter. Orthologous to human AQP1 (aquaporin 1 (Colton blood group)); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AQP-1; aquaporin-1; aquaporin-CHIP; CHIP28; delayed early response protein 2; DER2; growth factor-induced delayed early response protein; water channel protein for red blood cells and kidney proximal tubule
Homo sapiens (human) : AQP1 (aquaporin 1 (Colton blood group))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aqp1 (aquaporin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aqp1 (aquaporin 1 (Colton blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : AQP1 (aquaporin 1 (Colton blood group))
Canis lupus familiaris (dog) : AQP1 (aquaporin 1 (Colton blood group))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp1 (aquaporin 1 (Colton blood group))
Sus scrofa (pig) : AQP1 (aquaporin 1 (Colton blood group))
Chlorocebus sabaeus (African green monkey) : AQP1 (aquaporin 1 (Colton blood group))
Heterocephalus glaber (naked mole-rat) : Aqp1 (aquaporin 1 (Colton blood group))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl655,336,432 - 55,348,555 (+)EnsemblGRCm38mm10GRCm38
GRCm38655,336,299 - 55,348,555 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37655,286,293 - 55,298,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36655,266,010 - 55,278,133 (+)NCBImm8
Celera655,870,108 - 55,882,362 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Aqp1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10181
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.