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Gene: Aqp1 (aquaporin 1) Mus musculus
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Symbol: Aqp1
Name: aquaporin 1
Description: Exhibits ephrin receptor binding activity; potassium ion transmembrane transporter activity; and water transmembrane transporter activity. Involved in several processes, including corticotropin secretion; glomerular filtration; and metanephros development. Localizes to several cellular components, including basal plasma membrane; extracellular exosome; and symbiont-containing vacuole. Predicted to colocalize with symbiont-containing vacuole membrane. Is expressed in several structures, including alimentary system; metanephros; sensory organ; skeleton; and ureter. Orthologous to human AQP1 (aquaporin 1 (Colton blood group)); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AQP-1; aquaporin-1; aquaporin-CHIP; CHIP28; delayed early response protein 2; DER2; growth factor-induced delayed early response protein; water channel protein for red blood cells and kidney proximal tubule
Orthologs:
Homo sapiens (human) : AQP1 (aquaporin 1 (Colton blood group))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aqp1 (aquaporin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aqp1 (aquaporin 1 (Colton blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : AQP1 (aquaporin 1 (Colton blood group))
Canis lupus familiaris (dog) : AQP1 (aquaporin 1 (Colton blood group))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp1 (aquaporin 1 (Colton blood group))
Sus scrofa (pig) : AQP1 (aquaporin 1 (Colton blood group))
Chlorocebus sabaeus (African green monkey) : AQP1 (aquaporin 1 (Colton blood group))
Heterocephalus glaber (naked mole-rat) : Aqp1 (aquaporin 1 (Colton blood group))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl655,336,432 - 55,348,555 (+)EnsemblGRCm38mm10GRCm38
GRCm38655,336,299 - 55,348,555 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37655,286,293 - 55,298,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36655,266,010 - 55,278,133 (+)NCBImm8
Celera655,870,108 - 55,882,362 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Aqp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10181
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.