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Gene: Arrb2 (arrestin, beta 2) Mus musculus
Symbol: Arrb2
Name: arrestin, beta 2
Description: Exhibits protein kinase B binding activity. Involved in several processes, including negative regulation of cytokine production; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to localize to several cellular components, including the basolateral plasma membrane; cytoplasmic vesicle; and postsynaptic density. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human ARRB2 (arrestin beta 2); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; corticotropin-releasing hormone signaling pathway; INTERACTS WITH (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI326910; Arr3; arrestin 3; arrestin beta-2; AW122872; beta arr2; beta-arrestin-2; beta-arrestin2; RP23-42P20.7
Homo sapiens (human) : ARRB2 (arrestin beta 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arrb2 (arrestin, beta 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrb2 (arrestin beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRB2 (arrestin beta 2)
Canis lupus familiaris (dog) : ARRB2 (arrestin beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrb2 (arrestin beta 2)
Sus scrofa (pig) : ARRB2 (arrestin beta 2)
Chlorocebus sabaeus (green monkey) : ARRB2 (arrestin beta 2)
Heterocephalus glaber (naked mole-rat) : Arrb2 (arrestin beta 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1170,432,635 - 70,440,828 (+)Ensembl
GRCm381170,432,485 - 70,440,828 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,246,155 - 70,254,176 (+)NCBIGRCm37mm9NCBIm37
MGSCv361170,248,893 - 70,257,018 (+)NCBImm8
Celera1177,978,546 - 77,986,794 (+)NCBICelera
Cytogenetic Map11 B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Arrb2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10192
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.