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Gene: ATP7A (ATPase copper transporting alpha) Homo sapiens
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Symbol: ATP7A
Name: ATPase copper transporting alpha
CRRD ID: 10216
Description: Exhibits copper-dependent protein binding activity and cuprous ion binding activity. Involved in cellular copper ion homeostasis; copper ion transport; and positive regulation of oxidoreductase activity. Localizes to several cellular components, including basolateral plasma membrane; cytoplasmic vesicle; and trans-Golgi network. Implicated in Menkes disease; X-linked distal spinal muscular atrophy 3; cutis laxa; and occipital horn syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Cu++ transporting, alpha polypeptide; ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome); copper pump 1; copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; FLJ17790; Menkes disease-associated protein; MK; MNK; SMAX3
Orthologs:
Mus musculus (house mouse) : Atp7a (ATPase, Cu++ transporting, alpha polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp7a (ATPase copper transporting alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp7a (ATPase copper transporting alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP7A (ATPase copper transporting alpha)
Canis lupus familiaris (dog) : ATP7A (ATPase copper transporting alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp7a (ATPase copper transporting alpha)
Sus scrofa (pig) : ATP7A (ATPase copper transporting alpha)
Chlorocebus sabaeus (African green monkey) : ATP7A (ATPase copper transporting alpha)
Heterocephalus glaber (naked mole-rat) : Atp7a (ATPase copper transporting alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX77,910,656 - 78,050,395 (+)EnsemblGRCh38hg38GRCh38
GRCh38X77,910,693 - 78,050,395 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X77,166,194 - 77,305,892 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X77,052,876 - 77,192,208 (+)NCBINCBI36hg18NCBI36
Build 34X76,972,343 - 77,111,584NCBI
CeleraX77,407,059 - 77,546,975 (+)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX70,752,187 - 70,892,316 (+)NCBIHuRef
CHM1_1X77,058,841 - 77,198,586 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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