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Gene: Bax (BCL2-associated X protein) Mus musculus
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Symbol: Bax
Name: BCL2-associated X protein
Description: Exhibits Hsp70 protein binding activity; chaperone binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and regulation of apoptotic process. Localizes to several cellular components, including the BAX complex; endoplasmic reticulum; and mitochondrial outer membrane. Predicted to colocalize with the cell periphery. Human ortholog(s) of this gene implicated in ataxia telangiectasia; colon adenocarcinoma; and precursor lymphoblastic lymphoma/leukemia. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human BAX (BCL2 associated X, apoptosis regulator); PARTICIPATES IN ceramide signaling pathway; intrinsic apoptotic pathway; syndecan signaling pathway; INTERACTS WITH (+)-dexrazoxane; (+)-sesamin; (-)-citrinin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptosis regulator BAX
Orthologs:
Homo sapiens (human) : BAX (BCL2 associated X, apoptosis regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bax (BCL2 associated X, apoptosis regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bax (BCL2 associated X, apoptosis regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : BAX (BCL2 associated X, apoptosis regulator)
Canis lupus familiaris (dog) : BAX (BCL2 associated X, apoptosis regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bax (BCL2 associated X, apoptosis regulator)
Sus scrofa (pig) : BAX (BCL2 associated X, apoptosis regulator)
Chlorocebus sabaeus (green monkey) : BAX (BCL2 associated X, apoptosis regulator)
Heterocephalus glaber (naked mole-rat) : Bax (BCL2 associated X, apoptosis regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl745,461,697 - 45,466,898 (-)Ensembl
GRCm38745,461,695 - 45,466,903 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37752,717,065 - 52,722,268 (-)NCBIGRCm37mm9NCBIm37
MGSCv36745,329,744 - 45,334,864 (-)NCBImm8
Celera740,917,745 - 40,922,946 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model