Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: C8b (complement component 8, beta polypeptide) Mus musculus
Analyze
Symbol: C8b
Name: complement component 8, beta polypeptide
Description: Predicted to be involved in complement activation, alternative pathway; complement activation, classical pathway; and cytolysis. Predicted to localize to the extracellular space and membrane attack complex. Human ortholog(s) of this gene implicated in type II complement component 8 deficiency. Is expressed in brain; liver and biliary system; stomach; and testis. Orthologous to human C8B (complement C8 beta chain).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4930439B20Rik; AI595927; complement component 8 subunit beta; complement component 8, beta subunit; complement component C8 beta chain
Orthologs:
Homo sapiens (human) : C8B (complement C8 beta chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : C8b (complement C8 beta chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C8b (complement C8 beta chain)
Pan paniscus (bonobo/pygmy chimpanzee) : C8B (complement C8 beta chain)
Canis lupus familiaris (dog) : C8B (complement C8 beta chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C8b (complement C8 beta chain)
Sus scrofa (pig) : C8B (complement C8 beta chain)
Chlorocebus sabaeus (African green monkey) : C8B (complement C8 beta chain)
Heterocephalus glaber (naked mole-rat) : C8b (complement C8 beta chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4104,766,317 - 104,804,548 (+)Ensembl
GRCm384104,766,317 - 104,804,548 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374104,438,922 - 104,477,153 (+)NCBIGRCm37mm9NCBIm37
MGSCv364104,264,249 - 104,302,480 (+)NCBImm8
Celera4103,118,327 - 103,156,421 (+)NCBICelera
Cytogenetic Map4 C6NCBI
cM Map448.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on C8b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10264
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.