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Gene: CASR (calcium sensing receptor) Homo sapiens
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Symbol: CASR
Name: calcium sensing receptor
Description: Exhibits several functions, including amino acid binding activity; calcium ion binding activity; and protein homodimerization activity. Involved in several processes, including calcium ion import; cellular calcium ion homeostasis; and detection of calcium ion. Localizes to the integral component of plasma membrane. Implicated in several diseases, including autosomal dominant hypocalcemia (multiple); hypercalcemia (multiple); hyperparathyroidism (multiple); idiopathic generalized epilepsy 8; and nephrolithiasis. Biomarker of atherosclerosis; end stage renal failure; and secondary hyperparathyroidism.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium-sensing receptor; CAR; EIG8; extracellular calcium-sensing receptor; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; MGC138441; NSHPT; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor; parathyroid cell calcium-sensing receptor 1; PCAR1
Orthologs:
Mus musculus (house mouse) : Casr (calcium-sensing receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Casr (calcium-sensing receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casr (calcium sensing receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : CASR (calcium sensing receptor)
Canis lupus familiaris (dog) : CASR (calcium sensing receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casr (calcium sensing receptor)
Sus scrofa (pig) : CASR (calcium sensing receptor)
more info ...
Related Pseudogenes: VN2R17P   VN2R18P   VN2R19P   VN2R1P   VN2R3P   VN2R6P   VN2R7P   VN2R9P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3122,183,683 - 122,291,629 (+)Ensembl
GRCh383122,183,668 - 122,291,629 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373121,902,530 - 122,005,350 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363123,385,220 - 123,488,032 (+)NCBINCBI36hg18NCBI36
Build 343123,385,219 - 123,488,032NCBI
Celera3120,312,793 - 120,414,980 (+)NCBI
Cytogenetic Map3q13.33-q21.1NCBI
HuRef3119,276,062 - 119,378,878 (+)NCBIHuRef
CHM1_13121,866,087 - 121,968,904 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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