Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cd247 (CD247 antigen) Mus musculus
Analyze
Symbol: Cd247
Name: CD247 antigen
Description: Predicted to have identical protein binding activity and protein tyrosine kinase binding activity. Involved in T cell receptor signaling pathway; interleukin-2 production; and positive regulation of protein localization to cell surface. Localizes to alpha-beta T cell receptor complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD247 (CD247 molecule); PARTICIPATES IN interleukin-12 signaling pathway; Chagas disease pathway; T cell receptor signaling pathway; INTERACTS WITH 1,2-dichloroethane; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4930549J05Rik; A430104F18Rik; AW552088; Cd3; CD3 antigen, zeta polypeptide; CD3 zeta; CD3-eta; CD3-zeta; CD3-zeta/eta; Cd3h; Cd3z; CD3zeta; RIKEN cDNA A430104F18 gene; T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain; T-cell receptor zeta chain; T-cell surface glycoprotein CD3 eta chain; T-cell surface glycoprotein CD3 zeta chain; T3z; TCRk; Tcrz
Orthologs:
Homo sapiens (human) : CD247 (CD247 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd247 (Cd247 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd247 (CD247 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD247 (CD247 molecule)
Canis lupus familiaris (dog) : CD247 (CD247 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd247 (CD247 molecule)
Sus scrofa (pig) : CD247 (CD247 molecule)
Chlorocebus sabaeus (African green monkey) : CD247 (CD247 molecule)
Heterocephalus glaber (naked mole-rat) : Cd247 (CD247 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1165,788,681 - 165,877,277 (+)EnsemblGRCm38mm10GRCm38
GRCm381165,779,952 - 165,871,153 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371167,718,820 - 167,804,117 (+)NCBIGRCm37mm9NCBIm37
MGSCv361167,625,398 - 167,704,109 (+)NCBImm8
Celera1168,233,349 - 168,319,834 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map173.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Cd247
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10308
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.