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Gene: Cd44 (CD44 antigen) Mus musculus
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Symbol: Cd44
Name: CD44 antigen
CRRD ID: 10310
Description: Exhibits hyaluronic acid binding activity and type II transforming growth factor beta receptor binding activity. Contributes to cytokine binding activity and cytokine receptor activity. Involved in several processes, including negative regulation of T cell activation; negative regulation of signal transduction by p53 class mediator; and positive regulation of protein phosphorylation. Localizes to several cellular components, including basolateral plasma membrane; external side of plasma membrane; and macrophage migration inhibitory factor receptor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb; and urethra. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (Indian blood group)); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH (+)-pilocarpine; (-)-epigallocatechin 3-gallate; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU023126; AW121933; AW146109; ECMR-III; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HERM; HERMES; hermes antigen; HUTCH-I; hyaluronate receptor; Ly-2; Ly-24; lymphocyte antigen 24; Pgp; Pgp-1; PGP-I; phagocytic glycoprotein 1; phagocytic glycoprotein I
Orthologs:
Homo sapiens (human) : CD44 (CD44 molecule (Indian blood group))  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd44 (CD44 molecule (Indian blood group))  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd44 (CD44 molecule (Indian blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : CD44 (CD44 molecule (Indian blood group))
Canis lupus familiaris (dog) : CD44 (CD44 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd44 (CD44 molecule (Indian blood group))
Sus scrofa (pig) : CD44 (CD44 molecule)
Chlorocebus sabaeus (African green monkey) : CD44 (CD44 molecule (Indian blood group))
Heterocephalus glaber (naked mole-rat) : Cd44 (CD44 molecule (Indian blood group))
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl2102,811,141 - 102,901,665 (-)EnsemblGRCm38mm10GRCm38
GRCm382102,811,141 - 102,901,669 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372102,651,298 - 102,741,822 (-)NCBIGRCm37mm9NCBIm37
MGSCv362102,611,980 - 102,702,504 (-)NCBImm8
Celera2104,054,974 - 104,145,651 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd44
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10310
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.