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Gene: Cnr1 (cannabinoid receptor 1 (brain)) Mus musculus
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Symbol: Cnr1
Name: cannabinoid receptor 1 (brain)
Description: Exhibits cannabinoid receptor activity and voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. Involved in several processes, including axonal fasciculation; cannabinoid signaling pathway; and trans-synaptic signaling by endocannabinoid. Localizes to several cellular components, including GABA-ergic synapse; integral component of mitochondrial membrane; and integral component of presynaptic membrane. Predicted to colocalize with intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-type cannabinoid receptor; cannabinoid receptor 1; CB-R; CB1; CB1A; CB1B; CB1R; striatal cannabinoid receptor type 1 protein
Orthologs:
Homo sapiens (human) : CNR1 (cannabinoid receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cnr1 (cannabinoid receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnr1 (cannabinoid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNR1 (cannabinoid receptor 1)
Canis lupus familiaris (dog) : CNR1 (cannabinoid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnr1 (cannabinoid receptor 1)
Sus scrofa (pig) : CNR1 (cannabinoid receptor 1)
Chlorocebus sabaeus (African green monkey) : CNR1 (cannabinoid receptor 1)
Heterocephalus glaber (naked mole-rat) : Cnr1 (cannabinoid receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl433,924,593 - 33,948,831 (+)EnsemblGRCm38mm10GRCm38
GRCm38433,923,171 - 33,948,831 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37434,011,607 - 34,035,806 (+)NCBIGRCm37mm9NCBIm37
MGSCv36434,253,245 - 34,277,444 (+)NCBImm8
Celera433,679,304 - 33,703,476 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map416.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cnr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10370
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.