Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cnr1 (cannabinoid receptor 1 (brain)) Mus musculus
Symbol: Cnr1
Name: cannabinoid receptor 1 (brain)
Description: Exhibits cannabinoid receptor activity and voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels. Involved in several processes, including axonal fasciculation; cannabinoid signaling pathway; and trans-synaptic signaling by endocannabinoid. Localizes to several cellular components, including GABA-ergic synapse; integral component of mitochondrial membrane; and integral component of presynaptic membrane. Predicted to colocalize with intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH (S)-amphetamine; (S)-nicotine; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-type cannabinoid receptor; cannabinoid receptor 1; CB-R; CB1; CB1A; CB1B; CB1R; striatal cannabinoid receptor type 1 protein
Homo sapiens (human) : CNR1 (cannabinoid receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cnr1 (cannabinoid receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnr1 (cannabinoid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNR1 (cannabinoid receptor 1)
Canis lupus familiaris (dog) : CNR1 (cannabinoid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnr1 (cannabinoid receptor 1)
Sus scrofa (pig) : CNR1 (cannabinoid receptor 1)
Chlorocebus sabaeus (African green monkey) : CNR1 (cannabinoid receptor 1)
Heterocephalus glaber (naked mole-rat) : Cnr1 (cannabinoid receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl433,924,593 - 33,948,831 (+)EnsemblGRCm38mm10GRCm38
GRCm38433,923,171 - 33,948,831 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37434,011,607 - 34,035,806 (+)NCBIGRCm37mm9NCBIm37
MGSCv36434,253,245 - 34,277,444 (+)NCBImm8
Celera433,679,304 - 33,703,476 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map416.28NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cnr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10370
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.