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Gene: Crp (C-reactive protein, pentraxin-related) Mus musculus
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Symbol: Crp
Name: C-reactive protein, pentraxin-related
Description: Predicted to have several functions, including cholesterol binding activity; complement component C1q binding activity; and low-density lipoprotein particle binding activity. Predicted to be involved in several processes, including complement activation, classical pathway; negative regulation of macrophage derived foam cell differentiation; and regulation of reactive oxygen species metabolic process. Predicted to localize to the extracellular space; filopodium; and growth cone. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune hypersensitivity disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Is expressed in embryo and liver. Orthologous to human CRP (C-reactive protein); PARTICIPATES IN classical complement pathway; interleukin-6 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3',5'-cyclic AMP; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI255847; C-reactive protein; C-reactive protein, petaxin related
Orthologs:
Homo sapiens (human) : CRP (C-reactive protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crp (C-reactive protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CRP (C-reactive protein)
Canis lupus familiaris (dog) : CRP (C-reactive protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crp (C-reactive protein)
Sus scrofa (pig) : CRP (C-reactive protein, pentraxin-related)
Chlorocebus sabaeus (green monkey) : CRP (C-reactive protein)
Heterocephalus glaber (naked mole-rat) : Crp (C-reactive protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1172,698,055 - 172,833,031 (+)Ensembl
GRCm381172,698,056 - 172,699,966 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,628,187 - 174,630,097 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,534,741 - 174,536,635 (+)NCBImm8
Celera1175,548,254 - 175,550,142 (+)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map180.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Crp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10398
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.