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Gene: Crp (C-reactive protein, pentraxin-related) Mus musculus
Symbol: Crp
Name: C-reactive protein, pentraxin-related
Description: Predicted to have several functions, including cholesterol binding activity; complement component C1q binding activity; and low-density lipoprotein particle binding activity. Predicted to be involved in several processes, including complement activation, classical pathway; negative regulation of macrophage derived foam cell differentiation; and regulation of reactive oxygen species metabolic process. Predicted to localize to the extracellular space; filopodium; and growth cone. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune hypersensitivity disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Is expressed in embryo and liver. Orthologous to human CRP (C-reactive protein); PARTICIPATES IN classical complement pathway; interleukin-6 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3',5'-cyclic AMP; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI255847; C-reactive protein; C-reactive protein, petaxin related
Homo sapiens (human) : CRP (C-reactive protein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Crp (C-reactive protein)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CRP (C-reactive protein)
Canis lupus familiaris (dog) : CRP (C-reactive protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crp (C-reactive protein)
Sus scrofa (pig) : CRP (C-reactive protein, pentraxin-related)
Chlorocebus sabaeus (green monkey) : CRP (C-reactive protein)
Heterocephalus glaber (naked mole-rat) : Crp (C-reactive protein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1172,698,055 - 172,833,031 (+)Ensembl
GRCm381172,698,056 - 172,699,966 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371174,628,187 - 174,630,097 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,534,741 - 174,536,635 (+)NCBImm8
Celera1175,548,254 - 175,550,142 (+)NCBICelera
Cytogenetic Map1 H3NCBI
cM Map180.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Crp
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10398
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.