Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ctsc (cathepsin C) Mus musculus
Analyze
Symbol: Ctsc
Name: cathepsin C
Description: Exhibits cysteine-type peptidase activity; peptidase activator activity involved in apoptotic process; and serine-type endopeptidase activity. Involved in several processes, including T cell mediated cytotoxicity; negative regulation of myelination; and positive regulation of microglial cell activation. Localizes to cytoplasm. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Papillon-Lefevre disease and aggressive periodontitis. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human CTSC (cathepsin C).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI047818; CatC; cathepsin J; dipeptidyl peptidase 1; dipeptidyl peptidase I; dipeptidyl transferase; dipeptidyl-peptidase 1; dipeptidyl-peptidase I; dipeptidylpeptidase 1; DPP-I; DPP1; DPPI
Orthologs:
Homo sapiens (human) : CTSC (cathepsin C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ctsc (cathepsin C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ctsc (cathepsin C)
Pan paniscus (bonobo/pygmy chimpanzee) : CTSC (cathepsin C)
Canis lupus familiaris (dog) : CTSC (cathepsin C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ctsc (cathepsin C)
Sus scrofa (pig) : CTSC (cathepsin C)
Chlorocebus sabaeus (African green monkey) : CTSC (cathepsin C)
Heterocephalus glaber (naked mole-rat) : Ctsc (cathepsin C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl788,278,085 - 88,310,888 (+)EnsemblGRCm38mm10GRCm38
GRCm38788,278,024 - 88,315,861 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37795,426,603 - 95,459,385 (+)NCBIGRCm37mm9NCBIm37
MGSCv36788,153,327 - 88,186,080 (+)NCBImm8
Celera785,627,464 - 85,661,039 (+)NCBICelera
Cytogenetic Map7D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ctsc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10421
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.