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Gene: Cycs (cytochrome c, somatic) Mus musculus
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Symbol: Cycs
Name: cytochrome c, somatic
Description: Exhibits heme binding activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; hydrogen peroxide metabolic process; and regulation of protein binding activity. Localizes to the cytosol and mitochondrion. Human ortholog(s) of this gene implicated in cholangiocarcinoma; lung non-small cell carcinoma; pancreatic cancer; and thrombocytopenia. Is expressed in several structures, including central nervous system; jaw; limb; metanephros; and vibrissa. Orthologous to human CYCS (cytochrome c, somatic); PARTICIPATES IN cardiolipin metabolic pathway; ceramide signaling pathway; electron transport chain pathway; INTERACTS WITH (+)-dexrazoxane; (-)-citrinin; (-)-selegiline.
Type: protein-coding
RefSeq Status: VALIDATED
Orthologs:
Homo sapiens (human) : CYCS (cytochrome c, somatic)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cycs (cytochrome c, somatic)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023786 (cytochrome c, somatic)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986481 (cytochrome c)
Canis lupus familiaris (dog) : CYCS (cytochrome c, somatic)
Sus scrofa (pig) : CYCS (cytochrome c, somatic)
more info ...
Related Pseudogenes: Cycs-ps1   Cycs-ps2   Cycs-ps3   Gm10053   Gm10108   Gm10121   Gm19880   Gm19932   Gm48758  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38650,562,563 - 50,566,569 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37650,512,562 - 50,516,473 (-)NCBIGRCm37mm9NCBIm37
MGSCv36650,492,149 - 50,496,060 (-)NCBImm8
Celera651,079,647 - 51,083,558 (-)NCBICelera
Cytogenetic Map6 B2.3NCBI
cM Map624.32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cycs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 10425
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.